s-plus 7.0 (TIBCO)
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TIBCO
s-plus 7.0
S Plus 7.0, supplied by TIBCO, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/s-plus+7%2E0/s+plus+8+2/pmc04337691-119-13-15
Average 90 stars, based on 1 article reviews
S Plus 7.0, supplied by TIBCO, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/s-plus+7%2E0/s+plus+8+2/pmc04337691-119-13-15
Average 90 stars, based on 1 article reviews
s-plus 7.0 - by Bioz Stars,
2026-10
90/100 stars
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other:Article Title: Optimisation of imipenem regimens in patients with impaired renal function by pharmacokinetic-pharmacodynamic target attainment analysis of plasma and urinary concentration data. Article Snippet: In this study, a pharmacokinetic-pharmacodynamic (PK-PD) target attainment analysis of imipenem (IPM) in patients with impaired renal function was conducted.. IPM (500 mg) was administered via a 0.5-h or 1-h infusion to 27 patients with varying renal function.. A population PK model was developed by simultaneously fitting plasma and urinary concentration data. Article Title: Effect of axitinib on the QT interval in healthy volunteers. Article Snippet: alone.. Mean highest placebo-matched change from baseline in QTc was −3.0 [90 % confidence interval (CI) −5.4, −0.6] ms. At supratherapeutic axitinib exposures achieved with potent cytochrome P450 3A4/5 inhibition by ketoconazole, the model predicted mean QTc change of 6.5 (90 % CI 4.4–8.5) ms.. The slope population mean estimate was −0.331 (95 % CI −0.860, 0.198) ms·mL/μg for ketoconazole alone and 0.0725 (0.0445–0.1005) ms·mL/ng for axitinib in the presence of ketoconazole. Article Title: Integrin genetic variants and stage-specific tumor recurrence in patients with stage II and III colon cancer. Article Snippet: Integrins (ITGs) are key elements in cancer biology, regulating tumor growth, angiogenesis and lymphangiogenesis through interactions of the tumor cells with the microenvironment.. Moving from the hypothesis that ITGs could have different effects in stage II and III colon cancer, we tested whether a comprehensive panel of germline single-nucleotide polymorphisms (SNPs) in ITG genes could predict stage-specific time to tumor recurrence (TTR).. A total of 234 patients treated with 5-fluorouracil-based chemotherapy at the University of Southern California were included in this study. Article Title: A nude mouse model of obesity to study the mechanisms of resistance to aromatase inhibitors. Article Snippet: The tumor volumes were analyzed with Article Title: Identification of Five Chronic Obstructive Pulmonary Disease Subgroups with Different Prognoses in the ECLIPSE Cohort Using Cluster Analysis Article Snippet: Rationale: Chronic obstructive pulmonary disease (COPD) is a heterogeneous disease that likely includes clinically relevant subgroups.. Objectives: To identify subgroups of COPD in ECLIPSE subjects using cluster analysis and to assess clinically meaningful outcomes of the clusters during three years of longitudinal follow-up.. Methods: Factor analysis was used to reduce 41 variables determined at recruitment in 2,164 COPD patients to 13 main factors, and the variables with the highest loading were used for cluster analysis. Article Title: Population pharmacokinetics of pegaptanib sodium (Macugen ® ) in patients with diabetic macular edema Article Snippet: SAS 9.1.3 (Service Pack 4 XP_PRO platform; SAS Institute, Cary, NC, USA) and Article Title: Population Pharmacokinetic–Pharmacodynamic Target Attainment Analysis of Imipenem Plasma and Urine Data in Neonates and Children Article Snippet: Background: Population pharmacokinetic (PK)–pharmacodynamic target attainment analysis of imipenem was performed to elucidate the PK properties in neonates and children and to rationalize and optimize dosing regimens.. Methods: Population PK models were separately developed in neonates and children by simultaneously fitting plasma and urine data from 60 neonates and 39 children. the newly developed models were then used to estimate the probability of attaining the pharmacodynamic target (40% of the time above the minimum inhibitory concentration) against clinical isolates of common bacteria in pediatric patients.. Results: the data were best described by a 1-compartment model in neonates and a 2-compartment model in children, respectively. renal clearance in children (0.187 l/h/kg) was double that of neonates (0.0783 l/h/kg), whereas the volume of distribution at steady-state was approximately 1.8-fold larger in neonates (0.466 l/kg) than in children (0.260 l/kg). Article Title: Outcomes of Salvage Percutaneous Biliary Drainage after Occlusion of Endoscopic Stents. Article Snippet: Purpose: To describe outcomes of patients with malignant biliary obstruction who undergo salvage percutaneous biliary drainage after occlusion of endoscopic biliary stents.. Materials and Methods: A single-center retrospective review was performed of 47 patients (25 men, 22 women) who underwent percutaneous biliary drainage for recurrent obstruction after endoscopic stent placement between 2005 and 2015.. Primary malignancies were bile duct (n 1⁄4 13), colorectal (n 1⁄4 11), gallbladder (n 1⁄4 7), pancreas (n 1⁄4 5), hepatocellular (n 1⁄4 4), and other (n 1⁄4 7). |